Project outlines

Decreasing coronary artery disease (CAD) morbidity and mortality in the most cost-efficient manner is an important objective in public health. Moreover, identification of Acute Coronary Syndrome (ACS), procedures associated with the minimum in-hospital mortality, is an urgent requirement in order to update current guidelines, especially regarding the elderly.

EUROTRACS will allow EU policy makers to design national and international public health actions with this aim increasing, in turn, Europeans’ quality of life and longevity. Obtaining 10-year estimates of CAD mortality and CAD-associated costs will allow a more rational allocation of health resources in the European countries.

EUROTRACS is a project funded by the European Commission ("Consumers, Health and Food Executive Agency", former "Executive Agency for Health and Consumers"), under the Second Programme of Community Action in the Field of Public Health (2008–2013). It contributes to the Health Programme main objective “ to promote health, including the reduction of health inequalities”.

EUROTRACS main objective is to define a utility analysis (cost-effectiveness) in terms of cost per Quality-Adjusted Life Year (QALY) saved in two fields:

  1. reducing smoking, dyslipidaemia, and hypertension population prevalence by means of population interventions (including combined interventions) designed to prevent coronary artery disease incidence.
  2. optimally using coronary angiography and percutaneous intervention procedures in the management of patients with acute coronary syndrome (ACS) with special emphasis on the elderly (>64 years) to minimize the inequalities in this patient subgroup that has higher mortality than patients <65 years.

A predictive Internet-based model to interactively analyse the 10-year CAD event incidence, obtained by modifying the population prevalence of the targeted risk factors (smoking, cholesterol, hypertension), will be developed to identify the most cost-effective population interventions.

EUROTRACS results will thus give back to society in terms of longer-term benefits by contributing to reduce CAD and ACS morbidity, mortality and cost and age-dependent inequalities in ACS in-hospital treatment.

The project is organized in the following 7 Work Packages:

WP 1: Coordination of the project (Jaume Marrugat, PSMAR)

WP 2: Dissemination of the results (Marina Torre, ISS – Alessandro Corona, CINECA)

WP 3: Evaluation of the project (Christa Meisinger, HMGU)

WP 4: Estimation of number of CAD events prevented at 10 years by population interventions (Jean Ferrières, AEPMCV)

WP 5: Cost-effectiveness analysis of decreasing CAD incidence by reducing population risk factors prevalence (Jaume Marrugat, PSMAR)

WP 6: Estimation of procedure-associated in-hospital mortality and procedure cost in ACS (Danilo Fusco, DEASL)

WP 7: Cost-effectiveness analysis of ACS procedures that lower in-hospital fatality in patients older than 34 years (Jaume Marrugat, PSMAR)

Timetable: The project started on 01/06/2013 and ended on 31/05/2015.